bgp 15 Search Results


bgp 15  (MedChemExpress)
93
MedChemExpress bgp 15
Bgp 15, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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bgp 15  (Bio-Techne corporation)
93
Bio-Techne corporation bgp 15
Bgp 15, supplied by Bio-Techne corporation, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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bgp15  (Selleck Chemicals)
93
Selleck Chemicals bgp15
Fig. 5 Effects of leflunomide (10µM) and <t>BGP15</t> (15µM) on mitochondria-related proteins and senescence-related proteins, and oxygen consumption rate (OCR) in A549 cells in the presence and absence cigarette smoke extract (CSE). Mitochondria-related protein levels of MFN2 (A) and <t>OPA1</t> (B), phosphorylated-DRP1 (p-DRP1)/DRP1 (C), MFF (D), PINK1 (E), PARK2 (F), SQSTM1/p62 (G) and LC3b II/ LC3b I (H) and senescence-related protein levels of P16 (I), H2A.X (J) and Klotho (K) are measured by Western blot. N = 6 in each group. Every panel incorporates an illustrative Western blot image, and the data are presented as individual and mean values of each protein. Results of mitochondrial activities are presented as oxygen consumption rate (OCR) (L), and graphical analysis of basal (M) and maximal (N) respiration and on ATP production (O). N = 4 in each group. *p < 0.05, **p < 0.01, ***p < 0.001
Bgp15, supplied by Selleck Chemicals, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bgp15/product/Selleck Chemicals
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t3649  (TargetMol)
93
TargetMol t3649
Fig. 5 Effects of leflunomide (10µM) and <t>BGP15</t> (15µM) on mitochondria-related proteins and senescence-related proteins, and oxygen consumption rate (OCR) in A549 cells in the presence and absence cigarette smoke extract (CSE). Mitochondria-related protein levels of MFN2 (A) and <t>OPA1</t> (B), phosphorylated-DRP1 (p-DRP1)/DRP1 (C), MFF (D), PINK1 (E), PARK2 (F), SQSTM1/p62 (G) and LC3b II/ LC3b I (H) and senescence-related protein levels of P16 (I), H2A.X (J) and Klotho (K) are measured by Western blot. N = 6 in each group. Every panel incorporates an illustrative Western blot image, and the data are presented as individual and mean values of each protein. Results of mitochondrial activities are presented as oxygen consumption rate (OCR) (L), and graphical analysis of basal (M) and maximal (N) respiration and on ATP production (O). N = 4 in each group. *p < 0.05, **p < 0.01, ***p < 0.001
T3649, supplied by TargetMol, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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bgp 15  (Biosynth Carbosynth)
92
Biosynth Carbosynth bgp 15
Fig. 5 Effects of leflunomide (10µM) and <t>BGP15</t> (15µM) on mitochondria-related proteins and senescence-related proteins, and oxygen consumption rate (OCR) in A549 cells in the presence and absence cigarette smoke extract (CSE). Mitochondria-related protein levels of MFN2 (A) and <t>OPA1</t> (B), phosphorylated-DRP1 (p-DRP1)/DRP1 (C), MFF (D), PINK1 (E), PARK2 (F), SQSTM1/p62 (G) and LC3b II/ LC3b I (H) and senescence-related protein levels of P16 (I), H2A.X (J) and Klotho (K) are measured by Western blot. N = 6 in each group. Every panel incorporates an illustrative Western blot image, and the data are presented as individual and mean values of each protein. Results of mitochondrial activities are presented as oxygen consumption rate (OCR) (L), and graphical analysis of basal (M) and maximal (N) respiration and on ATP production (O). N = 4 in each group. *p < 0.05, **p < 0.01, ***p < 0.001
Bgp 15, supplied by Biosynth Carbosynth, used in various techniques. Bioz Stars score: 92/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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bgp-15  (N-Gene Research Laboratories)
90
N-Gene Research Laboratories bgp-15
Fig. 5 Effects of leflunomide (10µM) and <t>BGP15</t> (15µM) on mitochondria-related proteins and senescence-related proteins, and oxygen consumption rate (OCR) in A549 cells in the presence and absence cigarette smoke extract (CSE). Mitochondria-related protein levels of MFN2 (A) and <t>OPA1</t> (B), phosphorylated-DRP1 (p-DRP1)/DRP1 (C), MFF (D), PINK1 (E), PARK2 (F), SQSTM1/p62 (G) and LC3b II/ LC3b I (H) and senescence-related protein levels of P16 (I), H2A.X (J) and Klotho (K) are measured by Western blot. N = 6 in each group. Every panel incorporates an illustrative Western blot image, and the data are presented as individual and mean values of each protein. Results of mitochondrial activities are presented as oxygen consumption rate (OCR) (L), and graphical analysis of basal (M) and maximal (N) respiration and on ATP production (O). N = 4 in each group. *p < 0.05, **p < 0.01, ***p < 0.001
Bgp 15, supplied by N-Gene Research Laboratories, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bgp-15/product/N-Gene Research Laboratories
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bgp-15 cayman chemical  (Cayman Chemical)
90
Cayman Chemical bgp-15 cayman chemical
Fig. 5 Effects of leflunomide (10µM) and <t>BGP15</t> (15µM) on mitochondria-related proteins and senescence-related proteins, and oxygen consumption rate (OCR) in A549 cells in the presence and absence cigarette smoke extract (CSE). Mitochondria-related protein levels of MFN2 (A) and <t>OPA1</t> (B), phosphorylated-DRP1 (p-DRP1)/DRP1 (C), MFF (D), PINK1 (E), PARK2 (F), SQSTM1/p62 (G) and LC3b II/ LC3b I (H) and senescence-related protein levels of P16 (I), H2A.X (J) and Klotho (K) are measured by Western blot. N = 6 in each group. Every panel incorporates an illustrative Western blot image, and the data are presented as individual and mean values of each protein. Results of mitochondrial activities are presented as oxygen consumption rate (OCR) (L), and graphical analysis of basal (M) and maximal (N) respiration and on ATP production (O). N = 4 in each group. *p < 0.05, **p < 0.01, ***p < 0.001
Bgp 15 Cayman Chemical, supplied by Cayman Chemical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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o-[3-piperidino-2-hydroxy-1-propyl]-nicotinic acid amidoxime dihydrochloride (bgp-15)  (Halmosi GmbH)
90
Halmosi GmbH o-[3-piperidino-2-hydroxy-1-propyl]-nicotinic acid amidoxime dihydrochloride (bgp-15)
Fig. 5 Effects of leflunomide (10µM) and <t>BGP15</t> (15µM) on mitochondria-related proteins and senescence-related proteins, and oxygen consumption rate (OCR) in A549 cells in the presence and absence cigarette smoke extract (CSE). Mitochondria-related protein levels of MFN2 (A) and <t>OPA1</t> (B), phosphorylated-DRP1 (p-DRP1)/DRP1 (C), MFF (D), PINK1 (E), PARK2 (F), SQSTM1/p62 (G) and LC3b II/ LC3b I (H) and senescence-related protein levels of P16 (I), H2A.X (J) and Klotho (K) are measured by Western blot. N = 6 in each group. Every panel incorporates an illustrative Western blot image, and the data are presented as individual and mean values of each protein. Results of mitochondrial activities are presented as oxygen consumption rate (OCR) (L), and graphical analysis of basal (M) and maximal (N) respiration and on ATP production (O). N = 4 in each group. *p < 0.05, **p < 0.01, ***p < 0.001
O [3 Piperidino 2 Hydroxy 1 Propyl] Nicotinic Acid Amidoxime Dihydrochloride (Bgp 15), supplied by Halmosi GmbH, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/o-[3-piperidino-2-hydroxy-1-propyl]-nicotinic acid amidoxime dihydrochloride (bgp-15)/product/Halmosi GmbH
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hsp72 co-inducer bgp-15  (MultiTarget Pharmaceuticals)
90
MultiTarget Pharmaceuticals hsp72 co-inducer bgp-15
Fig. 5 Effects of leflunomide (10µM) and <t>BGP15</t> (15µM) on mitochondria-related proteins and senescence-related proteins, and oxygen consumption rate (OCR) in A549 cells in the presence and absence cigarette smoke extract (CSE). Mitochondria-related protein levels of MFN2 (A) and <t>OPA1</t> (B), phosphorylated-DRP1 (p-DRP1)/DRP1 (C), MFF (D), PINK1 (E), PARK2 (F), SQSTM1/p62 (G) and LC3b II/ LC3b I (H) and senescence-related protein levels of P16 (I), H2A.X (J) and Klotho (K) are measured by Western blot. N = 6 in each group. Every panel incorporates an illustrative Western blot image, and the data are presented as individual and mean values of each protein. Results of mitochondrial activities are presented as oxygen consumption rate (OCR) (L), and graphical analysis of basal (M) and maximal (N) respiration and on ATP production (O). N = 4 in each group. *p < 0.05, **p < 0.01, ***p < 0.001
Hsp72 Co Inducer Bgp 15, supplied by MultiTarget Pharmaceuticals, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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bgp-15  (Guiyang Xintian Pharmaceutical Co Ltd)
90
Guiyang Xintian Pharmaceutical Co Ltd bgp-15
Fig. 5 Effects of leflunomide (10µM) and <t>BGP15</t> (15µM) on mitochondria-related proteins and senescence-related proteins, and oxygen consumption rate (OCR) in A549 cells in the presence and absence cigarette smoke extract (CSE). Mitochondria-related protein levels of MFN2 (A) and <t>OPA1</t> (B), phosphorylated-DRP1 (p-DRP1)/DRP1 (C), MFF (D), PINK1 (E), PARK2 (F), SQSTM1/p62 (G) and LC3b II/ LC3b I (H) and senescence-related protein levels of P16 (I), H2A.X (J) and Klotho (K) are measured by Western blot. N = 6 in each group. Every panel incorporates an illustrative Western blot image, and the data are presented as individual and mean values of each protein. Results of mitochondrial activities are presented as oxygen consumption rate (OCR) (L), and graphical analysis of basal (M) and maximal (N) respiration and on ATP production (O). N = 4 in each group. *p < 0.05, **p < 0.01, ***p < 0.001
Bgp 15, supplied by Guiyang Xintian Pharmaceutical Co Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/bgp-15/product/Guiyang Xintian Pharmaceutical Co Ltd
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cytoprotective agent bgp-15  (Wolters Kluwer Health)
90
Wolters Kluwer Health cytoprotective agent bgp-15
Fig. 5 Effects of leflunomide (10µM) and <t>BGP15</t> (15µM) on mitochondria-related proteins and senescence-related proteins, and oxygen consumption rate (OCR) in A549 cells in the presence and absence cigarette smoke extract (CSE). Mitochondria-related protein levels of MFN2 (A) and <t>OPA1</t> (B), phosphorylated-DRP1 (p-DRP1)/DRP1 (C), MFF (D), PINK1 (E), PARK2 (F), SQSTM1/p62 (G) and LC3b II/ LC3b I (H) and senescence-related protein levels of P16 (I), H2A.X (J) and Klotho (K) are measured by Western blot. N = 6 in each group. Every panel incorporates an illustrative Western blot image, and the data are presented as individual and mean values of each protein. Results of mitochondrial activities are presented as oxygen consumption rate (OCR) (L), and graphical analysis of basal (M) and maximal (N) respiration and on ATP production (O). N = 4 in each group. *p < 0.05, **p < 0.01, ***p < 0.001
Cytoprotective Agent Bgp 15, supplied by Wolters Kluwer Health, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/cytoprotective agent bgp-15/product/Wolters Kluwer Health
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Image Search Results


Fig. 5 Effects of leflunomide (10µM) and BGP15 (15µM) on mitochondria-related proteins and senescence-related proteins, and oxygen consumption rate (OCR) in A549 cells in the presence and absence cigarette smoke extract (CSE). Mitochondria-related protein levels of MFN2 (A) and OPA1 (B), phosphorylated-DRP1 (p-DRP1)/DRP1 (C), MFF (D), PINK1 (E), PARK2 (F), SQSTM1/p62 (G) and LC3b II/ LC3b I (H) and senescence-related protein levels of P16 (I), H2A.X (J) and Klotho (K) are measured by Western blot. N = 6 in each group. Every panel incorporates an illustrative Western blot image, and the data are presented as individual and mean values of each protein. Results of mitochondrial activities are presented as oxygen consumption rate (OCR) (L), and graphical analysis of basal (M) and maximal (N) respiration and on ATP production (O). N = 4 in each group. *p < 0.05, **p < 0.01, ***p < 0.001

Journal: Respiratory research

Article Title: Role of mitochondrial fusion proteins MFN2 and OPA1 on lung cellular senescence in chronic obstructive pulmonary disease.

doi: 10.1186/s12931-023-02634-9

Figure Lengend Snippet: Fig. 5 Effects of leflunomide (10µM) and BGP15 (15µM) on mitochondria-related proteins and senescence-related proteins, and oxygen consumption rate (OCR) in A549 cells in the presence and absence cigarette smoke extract (CSE). Mitochondria-related protein levels of MFN2 (A) and OPA1 (B), phosphorylated-DRP1 (p-DRP1)/DRP1 (C), MFF (D), PINK1 (E), PARK2 (F), SQSTM1/p62 (G) and LC3b II/ LC3b I (H) and senescence-related protein levels of P16 (I), H2A.X (J) and Klotho (K) are measured by Western blot. N = 6 in each group. Every panel incorporates an illustrative Western blot image, and the data are presented as individual and mean values of each protein. Results of mitochondrial activities are presented as oxygen consumption rate (OCR) (L), and graphical analysis of basal (M) and maximal (N) respiration and on ATP production (O). N = 4 in each group. *p < 0.05, **p < 0.01, ***p < 0.001

Article Snippet: Prior to this, cells were pretreated with either 10 μM of leflunomide (MFN2 promoter) (#S1247, Selleck, Shanghai, China) or 15μM BGP15 (OPA1 promoter) (#S8370, Selleck) for a duration of 2 h. Following this pre-treatment, the cells were subsequently exposed to vehicle or CSE for another 24 h. Lentivirus transduction was used for genetic induction.

Techniques: Western Blot